Motifome comparison between modern human, Neanderthal and Denisovan
نویسندگان
چکیده
منابع مشابه
Neanderthal and Denisovan retroviruses in modern humans
distribution of the surrounding downwelling light. Deep-sea fishes that have instead evolved to detect bioluminescent point sources have eyes constructed accordingly, typically having a high spatial resolution provided by a retinal area of tightly packed visual cells arranged in a deep pit-like fovea. Their eyes, though, are often quite small, with pupils only as large as necessary to detect po...
متن کاملNovel Denisovan and Neanderthal Retroviruses
Following the recent availability of high-coverage genomes for Denisovan and Neanderthal hominids, we conducted a screen for endogenized retroviruses, identifying six novel, previously unreported HERV-K(HML2) elements (HERV-K is human endogenous retrovirus K). These elements are absent from the human genome (hg38) and appear to be unique to archaic hominids. These findings provide further evide...
متن کاملThe Mitonuclear Dimension of Neanderthal and Denisovan Ancestry in Modern Human Genomes
Some human populations interbred with Neanderthals and Denisovans, resulting in substantial contributions to modern-human genomes. Therefore, it is now possible to use genomic data to investigate mechanisms that shaped historical gene flow between humans and our closest hominin relatives. More generally, in eukaryotes, mitonuclear interactions have been argued to play a disproportionate role in...
متن کاملThe Combined Landscape of Denisovan and Neanderthal Ancestry in Present-Day Humans
Some present-day humans derive up to ∼5% [1] of their ancestry from archaic Denisovans, an even larger proportion than the ∼2% from Neanderthals [2]. We developed methods that can disambiguate the locations of segments of Denisovan and Neanderthal ancestry in present-day humans and applied them to 257 high-coverage genomes from 120 diverse populations, among which were 20 individual Oceanians w...
متن کاملNeanderthal genomics and the evolution of modern humans.
Humans possess unique physical and cognitive characteristics relative to other primates. Comparative analyses of the human and chimpanzee genomes are beginning to reveal sequence changes on the human lineage that may have contributed to the evolution of human traits. However, these studies cannot identify the genetic differences that distinguish modern humans from archaic human species. Here, I...
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ژورنال
عنوان ژورنال: BMC Genomics
سال: 2018
ISSN: 1471-2164
DOI: 10.1186/s12864-018-4710-1